Cancer pharmacodynamics and pharmacogenetics | Fundació Dr. Antonio Esteve

Autor

WE. Evans / MV. Relling

Any de publicació

2003

No disponible

La sèrie Pharmacotherapy revisited de la Fundació Dr. Antoni Esteve ha reunit en el seu cinquè volum els principals articles, en edició facsímil, que s’han publicat entre 1980 i 2000 sobre farmacodinàmica i farmacogenètica del càncer. Editat per William E. Evans i Mary V. Relling, del Departament de Ciències Farmacèutiques de l’Hospital St. Jude Children de Memphis, Estats Units, aquesta recopilació pretén incloure dins d’una mateixa publicació alguns dels avenços més importants que s’han realitzat en el camp de els investigacions contra el càncer i del tractament dels pacients.

Document complet
PDF complet	WE. Evans / MV. Relling	[wpdm type=”btn3″]
Capítols
Chapters	Acknowledgements	[wpdm id=27 type=”btn”]
Introduction	WE. Evans / MV. Relling	[wpdm id=29 type=”btn”]
Index		[wpdm id=28 type=”btn”]
1. Pharmacokinetics and dosage reduction of cis-diammine (1,1-cyclobutanedicarboxylato) platinum in patients with impaired renal function	MJ. Egorin / DA. Van Echo / SJ. Tipping / EA. Olman / MY. Whitacre / BW. Thompson / J. Aisner	[wpdm type=”btn3″]
2. Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect	WE. Evans / WR. Crom / M. Abromowitch / R. Dodge / AT. Look / WP. Bowman / SL. George / C-H. Pui	[wpdm type=”btn3″]
3. Clinical pharmacodynamics of continuous infusion teniposide: Systemic exposure as a determinant of response in a phase I trial	JH. Rodman / M. Abromowitch / JA. Sinkule / FA. Hayes / GK. Rivera / WE. Evans	[wpdm type=”btn3″]
4. Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation	GC. Yee / SG. Self / TR. McGuire / J. Carlin / JE. Sanders / HJ. Deeg	[wpdm type=”btn3″]
5. Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity	RB. Diasio / TL. Beavers / JT. Carpenter	[wpdm type=”btn3″]
6. Carboplatin dosage: Prospective evaluation of a simple formula based on renal function	AH. Calvert / DR. Newell / LA. Gumbrell / S. O\’Reilly / M. Burnell / FE. Boxall / ZH. Siddik / IR. Judson / ME. Gore / E. Wiltshaw	[wpdm type=”btn3″]
7. Pharmacokinetics of busulfan: Correlation with veno-occlusive disease in patients undergoing bone marrow transplantation	LB. Grochow / RJ. Jones / RB. Brundrett / HG. Braine / T-L. Chen / R. Saral / GW. Santos / OM. Colvin	[wpdm type=”btn3″]
8. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia	L. Lennard / JS. Lilleyman / J. Van Loon / RM. Weinshilboum	[wpdm type=”btn3″]
9. Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia	WE. Evans / M. Horner / YQ. Chu / D. Kalwinsky / WM. Roberts	[wpdm type=”btn3″]
10. Relation of systemic exposure to unbound etoposide and hematologic toxicity	CF. Stewart / SG. Arbuck / RA. Fleming / WE. Evans	[wpdm type=”btn3″]
11. Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer	DI. Jodrell / MJ. Egorin / RM. Canetta / P. Langenberg / EP. Goldbloom / JN. Burroughs / JL. Goodlow / S. Tan / E. Wiltshaw	[wpdm type=”btn3″]
12. Phase I and pharmacokinetic study of taxotere (RP 56976; NSC 628503) given as a short intravenous infusion	J-M. Extra / F. Rousseau / R. Bruno / M. Clavel / N. Le Bail / M. Marty	[wpdm type=”btn3″]
13. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy	V. Gandhi / E. Estey / MJ. Keating / W. Plunkett	[wpdm type=”btn3″]
14. Relationship between fluorouracil systemic exposure and tumor response and patient survival	G. Milano / MC. Etienne / N. Renée / A. Thyss / M. Schneider / A. Ramaioli / F. Demard	[wpdm type=”btn3″]
15. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia	TW. Synold / MV. Relling / JM. Boyett / GK. Rivera / JT. Sandlund / H. Mahmoud / WM. Crist / C-H. Pui / WE. Evans	[wpdm type=”btn3″]
16. Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors	DS. Sonnichsen / CA. Hurwitz / CB. Pratt / JJ. Shuster / MV. Relling	[wpdm type=”btn3″]
17. Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans	L. Gianni / CM. Kearns / A. Giani / G. Capri / L. Viganó / A. Locatelli / G. Bonadonna / MJ. Egorin	[wpdm type=”btn3″]
18. Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance	CR. Yates / EY. Krynetski / T. Loennechen / MY. Fessing / H-L. Tai / C-H. Pui / MV. Relling / WE. Evans	[wpdm type=”btn3″]
19. Marrow transplantation for chronic myeloid leukemia: The influence of plasma busulfan levels on the outcome of transplantation	JT. Slattery / RA. Clift / CD. Buckner / J. Radich / B. Storer / WI. Bensinger et al.	[wpdm type=”btn3″]
20. Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia	WE. Evans / MV. Relling / JH. Rodman / WR. Crom / JM. Boyett / C-H. Pui	[wpdm type=”btn3″]
21. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes	L. Iyer / CD. King / PF. Whitington / MD. Green / SK. Roy / TR. Tephly / BL. Coffman / MJ. Ratain	[wpdm type=”btn3″]
22. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus	MV. Relling / ML. Hancock / GK. Rivera / JT. Sandlund / RC. Ribeiro / EY. Krynetski / C-H. Pui / WE. Evans	[wpdm type=”btn3″]

Cancer pharmacodynamics and pharmacogenetics Introduction
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Cancer pharmacodynamics and pharmacogenetics Index
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Cancer pharmacodynamics and pharmacogenetics Acknowledgements
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