Kinetics of drug action in disease states | Fundació Dr. Antonio Esteve

Autor

G. Levy

Any de publicació

2002

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Kinetics of drug action in diseases states és el quart volum de Pharmacotherapy revisited: an Esteve Foundation Series. Gerhard Levy, de la Universitat Estatal de Nova York a Buffalo, recopila 44 articles publicats a diferents revistes de l’especialitat. Aquests treballs, que apareixen en edició facsímil, desenvolupen diferents aspectes sobre l’estudi de la cinètica dels fàrmacs en models experimentals de diverses malalties.

Document complet
PDF complet	G. Levy	[wpdm type=”btn3″]
Capítols
Acknowledgements		[wpdm id=24 type=”btn”]
Introduction	G. Levy	[wpdm id=26 type=”btn”]
Index		[wpdm id=25 type=”btn”]
1. Kinetics of drug action in disease states. I. Effect of infusion rate on phenobarbital concentrations in serum, brain and cerebrospinal fluid of normal rats at onset of loss of righting reflex	M. Danhof / G. Levy	[wpdm type=”btn3″]
2. Kinetics of drug action in disease states. II. Effect of experimental renal dysfunction on phenobarbital concentrations in rats at onset of loss of righting reflex	M. Danhof / M. Hisaoka / G. Levy	[wpdm type=”btn3″]
3. Kinetics of drug action in disease states. III. Effect of pregnancy on the relationship between phenytoin concentration and antiseizure activity in rats	RC. Chou / G. Levy	[wpdm type=”btn3″]
4. Kinetics of drug action in disease states. IV. Effect of pregnancy on phenobarbital concentrations at onset of loss of righting reflex in rats	M. Danhof / G. Levy	[wpdm type=”btn3″]
5. Kinetics of drug action in disease states. V. Acute effect of urea infusion on phenobarbital concentrations in rats at onset of loss of righting reflex	M. Danhof / G. Levy	[wpdm type=”btn3″]
6. Kinetics of drug action in disease states. VI. Effect of experimental diabetes on phenobarbital concentrations in rats at onset of loss of righting reflex	M. Danhof / M. Hisaoka / G. Levy	[wpdm type=”btn3″]
7. Kinetics of drug action in disease states. VII. Effect of experimental renal dysfunction on the pharmacodynamics of ethanol in rats	M. Hisaoka / M. Danhof / G. Levy	[wpdm type=”btn3″]
8. Effect of pregnancy on ethanol concentrations at onset of loss of righting reflex in rats	M. Hisaoka / G. Levy	[wpdm type=”btn3″]
9. Kinetics of drug action in disease states. IX. Effect of experimental fever on phenobarbital concentrations at onset of loss of righting reflex in rats	M. Hisaoka / G. Levy	[wpdm type=”btn3″]
10. Pharmacodynamics of the hypnotic effect of salicylamide in rats	ME. Morris / G. Levy	[wpdm type=”btn3″]
11. Kinetics of drug action in disease states. XI. Effect of nicotine on the pharmacodynamics and pharmacokinetics of phenobarbital and ethanol in rats	M. Hisaoka / G. Levy	[wpdm type=”btn3″]
12. Kinetics of drug action in disease states. XII. Effect of experimental liver diseases on the pharmacodynamics of phenobarbital and ethanol in rats	M. Danhof / M. Hisaoka / G. Levy	[wpdm type=”btn3″]
13. Kinetics of drug action in disease states. XIII. Effect of dialyzable component(s) of uremic blood on phenobarbital concentrations in rat at onset of loss of righting reflex	M. Hisaoka / G. Levy	[wpdm type=”btn3″]
14. Kinetics of drug action in disease states. XIV. Effect of infusion rate on pentylenetetrazol concentrations in serum, brain and cerebrospinal fluid of rats at onset of convulsions	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
15. Kinetics of drug action in disease states. XV. Effect of pregnancy on the convulsive activity of pentylenetetrazol in rats	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
16. Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
17. Chronic theophylline administration has no apparent effect on theophylline concentrations required to produce seizures in rats	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
18. Kinetics of drug action in disease states. XVIII. Effect of experimental renal failure on the pharmacodynamics of theophylline-induced seizures in rats	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
19. Kinetics of drug action in disease states. XIX. Effect of experimental liver disease on the neurotoxicity of theophylline in rats	IM. Ramzan / M. Yasuhara / G. Levy	[wpdm type=”btn3″]
20. Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition	S. Wanwimolruk / G. Levy	[wpdm type=”btn3″]
21. Kinetics of drug action in disease states. XXI. Relationship between drug infusion rate and dose required to produce a pharmacologic effect	PM. Klockowski / G. Levy	[wpdm type=”btn3″]
22. Kinetics of drug action in disease states. XXII. Effects of contraceptive steroids on the pharmacodynamics of ethanol in rats	S. Wanwimolruk / G. Levy	[wpdm type=”btn3″]
23. Kinetics of drug action in disease states. XXIII. Effect of acute hypovolemia on the pharmacodynamics of phenobarbital in rats	PM. Klockowski / G. Levy	[wpdm type=”btn3″]
24. Kinetics of drug action in disease states. XXIV. Pharmacodynamics of diazepam and its active metabolites in rats	PM. Klockowski / G. Levy	[wpdm type=”btn3″]
25. Kinetics of drug action in disease states. XXV. Effect of experimental hypovolemia on the pharmacodynamics and pharmacokinetics of desmethyldiazepam	PM. Klockowski / G. Levy	[wpdm type=”btn3″]
26. Kinetics of drug action in disease states. XXVI. Effect of fever on the pharmacodynamics of theophylline-induced seizures in rats	M. Yasuhara / G. Levy	[wpdm type=”btn3″]
27. Kinetics of drug action in disease states. XXVII. Effect of experimental renal failure on the pharmacodynamics of zoxazolamine and chlorzoxazone	M. Yasuhara / G. Levy	[wpdm type=”btn3″]
28. Kinetics of drug action in disease states. XXVIII. Effect of acute hypovolemia on theophylline-induced neurotoxicity in rats	M. Yasuhara / G. Levy	[wpdm type=”btn3″]
29. Kinetics of drug action in disease states. XXIX. Effect of experimental nephrotic syndrome on the pharmacodynamics of heptabarbital: Implications of severe hypoalbuminemia	A. Hoffman / G. Levy	[wpdm type=”btn3″]
30. Experimental renal dysfunction increases pain sensitivity in rats	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
31. Kinetics of drug action in disease states. XXXI. Effect of experimental hyperthyroidism on the hypnotic activity of a benzodiazepine (oxazepam) in rats	JS. Walker / PM. Klockowski / G. Levy	[wpdm type=”btn3″]
32. Kinetics of drug action in disease states. XXXII. Effect of experimental hypertension on the pharmacodynamics of phenobarbital in rats	JS. Walker / G. Levy	[wpdm type=”btn3″]
33. Kinetics of drug action in disease states. XXXIII. Disparate effects of pentylenetetrazol in rats as a function of renal disease model and pharmacologic endpoint	IM. Ramzan / G. Levy	[wpdm type=”btn3″]
34. Kinetics of drug action in disease states. XXXIV. Effect of experimental thyroid disorders on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol	JS. Walker / G. Levy	[wpdm type=”btn3″]
35. Kinetics of drug action in disease states. XXXV. Effect of hypovolemia on the pharmacodynamics of zoxazolamine in rats	S. Sato / G. Levy	[wpdm type=”btn3″]
36. Kinetics of drug action in disease states. XXXVI. Effect of cyclosporine on the pharmacodynamics and pharmacokinetics of a barbiturate (heptabarbital) in rats	A. Hoffman / G. Levy	[wpdm type=”btn3″]
37. Kinetics of drug action in disease states. XXXVII. Effects of acute fluid overload and water deprivation on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline in rats	J. Zhi / G. Levy	[wpdm type=”btn3″]
38. Kinetics of drug action in disease states. XXXVIII. Effect of body temperature on the convulsant activity of pentylenetetrazol in rats	JS. Walker / G. Levy	[wpdm type=”btn3″]
39. Kinetics of drug action in disease states. XXXIX. Effect of orally administered activated charcoal on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline administered intravenously to rats with renal failure	A. Hoffman / G. Levy	[wpdm type=”btn3″]
40. Kinetics of drug action in disease states. XL. Effect of the dialyzable component(s) of uremic blood on theophylline neurotoxicity in rats	A. Hoffman / G. Levy	[wpdm type=”btn3″]
41. Kinetics of drug action in disease states. XLI. Effect of adrenalectomy on the hypnotic activity of phenobarbital, the neurotoxicity of theophylline and pain sensitivity in rats	A. Hoffman / G. Levy	[wpdm type=”btn3″]
42. Kinetics of drug action disease states. XLII. Effect of repeated blood sampling on the pharmacodynamics of phenobarbital in rats	A. Hoffman / PM. Klockowski / G. Levy	[wpdm type=”btn3″]
43. Kinetics of drug action in disease states. XLIII. Potentiating effect of L-tryptophan on the hypnotic action of phenobarbital and ethanol in rats	TCM. Wilson / G. Levy	[wpdm type=”btn3″]
44. Effect of hepatic cirrhosis on the pharmacodynamics and pharmacokinetics of mivacurium in humans	G. Levy	[wpdm type=”btn3″]
45. Kinetics of drug action in disease states. XLV. Effect of elevated plasma creatinine concentrations on the hypnotic action of phenobarbital in normal rats	TCM. Wilson / G. Levy	[wpdm type=”btn3″]

Kinetics of drug action in disease states Acknowledgements
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Kinetics of drug action in disease states Introduction
G. Levy
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Kinetics of drug action in disease states Index
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