Francisco Grande Covián, emeritus professor of the Department of Biochemistry of the Faculty of Sciences of the University of Zaragoza, imparted the lecture Nutrients and drugs at the Royal Academy of Pharmacy. This was the fifth annual lecture organized by the Esteve Foundation and was held on May 26, 1988. Prof. Grande Covián’s name is strongly linked to the progress of the physiology –and particularly the science– of nutrition, on account of his contributions in the fields of muscle biochemistry and physiology, fatty acid dehydrogenation enzymes, brain and cardiac metabolism, biochemical effects of diets and nutritional restrictions, or hormonal regulation of fatty acid mobilization.