The 12th Esteve Foundation Symposium was held from 4-7 October 2006 in S’Agaro (Catalonia, Spain) on the topic Molecular Biology and Pharmacology of Tissue Repair with 21 speakers from 7 countries all over the world. It was chaired by Sabine Werner, from the Institute of Cell Biology of Zurich (Switzerland) and this was the program of the three days meeting:

Infection, inflammation and repair. Chaired by Sabine Werner

1. Imaging repair and inflammation on flies, fish and mice
Paul Martin. University of Bristol
2. Endothelial cell contacts in inflammation and angiogenesis
Dietmar Vestweber. Max-Planck Institute for Molecular Biomedicine
3. Antimicrobial peptides – effector molecules of the epithelial defense system
Jens-Michael Schröder. University Hospital Schleswig-Holstein
4. Molecular analysis of the tumor suppressor function of CYLD
Reinhard Fässler. Max-Planck Institute for Biochemistry

Skin repair. Chaired by Judith Abraham, from Chiron Corporation

5. Notch signaling in control of keratinocyte self renewal and tumorigenesis?
Paolo Dotto. Université de Lausanne
6. Epithelial-stromal interactions control skin tissue regeneration
Norbert Fusenig. German Cancer Research Center
7. Roles of PPARs in wound healing
Walter Wahli. Université de Lausanne
8. Novel actions of cardiac ankyrin repeat protein
Jeffrey Davidson. Vanderbilt University School of Medicine

Repair of bone / cartilage / muscle. Chaired by Pura Muñoz, fromCentre de Regulació Genòmica of Barcelona

9. FGF signaling in cartilage and bone
David Ornitz. University of Washington
10. Pathomechanisms of osteoarthritis
Martin Lotz. The Scripps Research Institute
11. Skeletal repair using adipose derived cells
Michael Longaker. Stanford University School of Medicine
12. How to improve muscle regeneration
Antonio Musarò. Universita’ degli Studi di Roma La Sapienza

Liver / lung repair and fibrosis. Chaired by Jeffrey Davidson, from the Vanderbilt University School of Medicine

13. TGF-β and Smad3 link inflammation to progressive fibrosis
Jack Gauldie. McMaster University
14. Role of metalloproteinases in epithelial repair
William Parks. University of Washington
15. Interactions between ECM and innate immunity in tissue injury and repair
Paul Noble. Duke University
16. Rebuilding the liver with adult hepatic and embryonic stem cells
Snorri Thorgeirsson. National Cancer Institute
17. EGF receptor function in health and disease
Maria Sibilia. University of Viena

Repair of the CNS and PNS. Chaired by Kate Nobes, from the University of Bristol

18. Neuronal stem cells
Ron McKay. Porter Neuroscience Research Science
19. Repair of the injured central nervous system
Martin Schwab. University of Zurich
20. The Nrf2-ARE pathway: a potential therapeutic target for neurodegenerative diseases
Jeffrey Jonson. University of Wisconsin
21. Rewiring the injured CNS: novel growth factors, signaling pathways, and combinatorial treatments
Larry Benowitz. Children’s Hospital Boston