The second round table organized by the Esteve Foundation was held on April 18, 1985 in Barcelona, with the title Problems arising from the treatment of severe infections caused by S. Aureus. This discussion was moderated by Guillem Verger, from the Unit of Infectious Diseases of the Sant Pau Hospital of Barcelona, and its content is published in Dr. Antonio Esteve’s Monograph number 2. This includes some of the severe infections caused by this bacterium, such as skin infections and osteomyelitis, as well as a few measures such as antibiotic treatment.