G protein‐coupled receptor signaling complexes: functional and pharmacological perspectives

G protein-coupled receptors (GPCRs) constitute a large superfamily of proteins that respond to a variety of extracellular stimuli ranging from photons and small molecules to peptides and proteins, such as hormones, neurotransmitters and paracrine agents which activate transduction pathways of signals and, finally, give rise to specific cellular responses. In humans there are more than…

2020

Pharmacogenomics: Advances and Challenges

Pharmacogenomics is the study of the role of the genome in drug response. It analyzes how the genetic makeup of an individual affects his/her response to drugs. The Dr. Antoni Esteve Foundation organized its ninth Esteve Foundation Discussion Group by bringing together nine of the leading experts in the field the past 23 and 24…

2019

Meet the expert: Gordon Guyatt

With more than 1,200 scientific papers published in such periodicals as The New England Journal of Medicine, The Lancet and JAMA (Journal of the American Medical Association), Gordon Guyatt has established himself as a prominent figure in the history of medicine. A professor in McMaster University’s department of clinical epidemiology and biostatistics in Canada, he…

2018

Workshop Soft skills in medical education: The role of medical humanities in the twenty-first century

Medical humanities not only help to understand the real nature of medicine and health, but also enable health professionals to treat their patients with respect and dignity and to provide more empathetic care. In this sense, they have become an essential tool to develop so-called transversal skills in the education environment. The Esteve Foundation organized…

2017

Meet the expert: Patangi K. Rangachari

His scientific research has focused on the effects of inflammatory mediators on ion transport, but if there is one thing that has made Patangi K. Rangachari, emeritus professor at McMaster University in Canada, world famous, it is his contributions to university education. The Esteve Foundation instigated a new international activity, Meet the Expert, with the…

2017

Symposia

International symposia attempt to encourage contact between scientists by discussing a topic of relevant multidisciplinary content. These meetings can only be accessed via invitation of a very small number of participants (maximum of 30), and discussion-fostering topics are provided. The duration is of three days, with a maximum number of around 25 submitters. These prepare manuscripts…

New perspectives on D-Amino Acids

Proteins are the most abundant biological cellular macromolcules and structurally characterized by being formed from a group of 20 precursor molecules, known as amino acids. The grouping and combination of these amino acids enable peptides, oligopeptides and polypetides to be formed, to construct larger structures, which are strictly speaking proteins. Although up until now it…

2014