Author
S. Erill
Dr.Antonio Esteve Foundation
TORRE ESTEVEPasseig de la Zona Franca, 109
08038 Barcelona
Tel:
93 433 53 20
E-mail:
fundacion@esteve.org
Dr. Louis Lasagna’s contribution to fostering clinical pharmacology is unquestionable. After graduating from Rutgers University in 1943 and earning his doctor’s degree four years later from Columbia University, Dr. Lasagna revolutionized the world of medicinal products. As from the mid-fifties, he investigated the influence of the placebo effect in the efficacy of drugs by means of clinical trials. Dr. Lasagna was especially interested in analgesia, euthanasia, hypnosis and the problems related to the research and development of new medicinal products. He also determined the need for ethical and regulatory aspects in clinical research.
All these contributions to the field of clinical pharmacology justified that the first volume of the Pharmacotherapy Revisited series be entirely dedicated to Dr. Louis Lasagna. Sergio Erill, director of the Foundation, compiled at his own discretion Dr. Lasagna’s most relevant articles (published between 1954 and 1987), which proved indispensable to the progress of clinical pharmacology. Twenty-six articles were finally selected in this book, as originally published in a facsimile edition.
Full document | ||
Full PDF | S. Erill | [wpdm type=”btn3″] |
Chapters | ||
Capitulos | S. Erill | [wpdm id=14 type=”btn”] |
Index | [wpdm id=16 type=”btn”] | |
1. A study of the placebo response | L. Lasagna / F. Mosteller / JM. von Felsinger / HK. Beecher | [wpdm type=”btn3″] |
2. The volunteer subject in research | L. Lasagna / JM. von Felsinger | [wpdm type=”btn3″] |
3. The controlled clinical trial: Theory and practice | L. Lasagna | [wpdm type=”btn3″] |
4. Further studies on the \”pharmacology\” of placebo administration | L. Lasagna / VG. Laties / JL. Dohan | [wpdm type=”btn3″] |
5. Gripesmanship: A positive approach | L. Lasagna | [wpdm type=”btn3″] |
6. The effect of dosage regimen on the diuretic efficacy of chlorothiazide in human subjects | J. Murphy / W. Casey / L. Lasagna | [wpdm type=”btn3″] |
7. A matter of perspective | L. Lasagna | [wpdm type=”btn3″] |
8. The diseases drugs cause | L. Lasagna | [wpdm type=”btn3″] |
9. Clinical pharmacology: Present status and future development | L. Lasagna | [wpdm type=”btn3″] |
10. The clinical pharmacologist as a servant of society | L. Lasagna | [wpdm type=”btn3″] |
11. Obtaining informed consent: Form or substance | LC. Epstein / L. Lasagna | [wpdm type=”btn3″] |
12. The pharmaceutical revolution: Its impact on science and society | L. Lasagna | [wpdm type=”btn3″] |
13. Prescribing patterns of physicians | PD. Stolley / L. Lasagna | [wpdm type=”btn3″] |
14. Drug evaluation problems in academic and other contexts | L. Lasagna | [wpdm type=”btn3″] |
15. Fault and default | L. Lasagna | [wpdm type=”btn3″] |
16. A plea for the \”naturalistic\” study of medicines | L. Lasagna | [wpdm type=”btn3″] |
17. The normal volunteer in clinical investigation: How rigid should selection criteria be? | P. Joubert / L. Rivera-Calimlim / L. Lasagna | [wpdm type=”btn3″] |
18. Patient package inserts. I. Nature, notions, and needs | P. Joubert / L. Lasagna | [wpdm type=”btn3″] |
19. Patient package inserts. II. Toward a rational patient package insert | P. Joubert / L. Lasagna | [wpdm type=”btn3″] |
20. Toward the operational indentification of adverse drug reactions | FE. Karch / L. Lasagna | [wpdm type=”btn3″] |
21. Free-living volunteer\’s motivation and attitudes toward pharmacologic studies in man | M. Hassar / R. Pocelinko / M. Weintraub / D. Nelson / G. Thomas / L. Lasagna | [wpdm type=”btn3″] |
22. The development and regulation of new medications | L. Lasagna | [wpdm type=”btn3″] |
23. Placebos and controlled trials under attack | L. Lasagna | [wpdm type=”btn3″] |
24. Statistics: A new co-carcinogen | L. Lasagna | [wpdm type=”btn3″] |
25. Historical controls: The practitioner\’s clinical trials | L. Lasagna | [wpdm type=”btn3″] |
26. On assuring pharmacotherapeutic progress in the 21st century | L. Lasagna | [wpdm type=”btn3″] |