Author
The third international symposium organized by the Esteve Foundation resulted in this new publication of the Esteve Foundation Symposia series, focusing on the dose-response relationship in clinical pharmacology. Professors Lasagna, Erill and Naranjo edited the book gathering the different submissions and their respective discussions. Finding a clear relationship between the dose or concentration of a drug and a given effect is considered to be a reliable way of attributing the drug’s action. The study of this relationship allows both in-depth studies of the drug’s characteristics and the possibility of quantifying or even guessing possible effects of non-evaluated doses.
| Chapters | ||
| Preface | L. Lasagna / S. Erill / CA. Naranjo | [wpdm id=120 type=”btn”] |
| List of participants | [wpdm id=121 type=”btn”] | |
| Contents | [wpdm id=122 type=”btn”] | |
| 1. Pharmacometry in man: The state of the art | L. Lasagna | [wpdm id=98 type=”btn”] |
| 2. Log dose-response curves in basic and clinical pharmacology | L. Lemberger | [wpdm id=99 type=”btn”] |
| 3. Circadian chromopharmacologic modulation of dose-response relationshipgs in rodents and in men | A. Reinberg / F. Levi | [wpdm id=100 type=”btn”] |
| 4. Dose-response relationships in normal versus diseased subjects | M. Orme | [wpdm id=101 type=”btn”] |
| 5. Pharmacokinetic modulation of the dose-response relationship | JG. Baxter / JA. Barnett / D. Lalka | [wpdm id=102 type=”btn”] |
| 6. Considerations of dose-response with centrally-acting drugs | A. Nicholson / PA. Pascoe / MB. Spencer | [wpdm id=103 type=”btn”] |
| 7. Dose-response relationships in drug dependence in humans | CA. Naranjo / UE. Busto | [wpdm id=104 type=”btn”] |
| 8. The dose-response curve in indirectly acting drugs | P. du Souich / P. Larochelle / S. Marleau / J. Cusson | [wpdm id=105 type=”btn”] |
| 9. Dose response relationship in toxicology | LF. Prescott | [wpdm id=106 type=”btn”] |
| 10. The dose response relationship and clinical trials | C. Maxwell | [wpdm id=107 type=”btn”] |
| 11. Dose-response and registration of new drugs | R. Temple | [wpdm id=108 type=”btn”] |
| 12. Dose-response relationship in respect of biochemical effects of drugs and the problem of adaptive responses | DG. Grahame-Smith | [wpdm id=109 type=”btn”] |
| 13. Effect of age in the dose response curve | P. Lucio | [wpdm id=110 type=”btn”] |
| 14. Dose-response relationship and therapeutic drug monitoring | E. Perucca / F. Pisani | [wpdm id=111 type=”btn”] |
| 15. An epidemiological approach to dose-response relationship | U. Busto / CA. Naranjo | [wpdm id=112 type=”btn”] |
| 16. Dose response effects in analgesiometry: clinical vs experimental pain | HJ. McQuay | [wpdm id=113 type=”btn”] |
| 17. The dose-response curves in essential hypertension | P. Larochelle | [wpdm id=114 type=”btn”] |
| 18. The dose response relationship in anesthesiology | WS. Nimmo | [wpdm id=115 type=”btn”] |
| 19. Pharmacological dose-response curves in gastrointestinal therapy | TR. Weihrauch / P. Demol | [wpdm id=116 type=”btn”] |
| 20. Dose-response relationships in antimicrobial therapy | AM. Geddes | [wpdm id=117 type=”btn”] |
| 21. Dose response relationships in pshychopharmacology | LF. Gram | [wpdm id=118 type=”btn”] |
| 22. The relation between dose and response to diagnostic drugs | EA. Carr Jr. / JM. Gona / M. Carroll / RJ. Kurland | [wpdm id=119 type=”btn”] |
- 1. Pharmacometry in man: The state of the art
- L. Lasagna
- Download
- 9. Dose response relationship in toxicology
- LF. Prescott
- Download
- 17. The dose-response curves in essential hypertension
- P. Larochelle
- Download
- 2. Log dose-response curves in basic and clinical pharmacology
- L. Lemberger
- Download
- 10. The dose response relationship and clinical trials
- C. Maxwell
- Download
- 18. The dose response relationship in anesthesiology
- WS. Nimmo
- Download
- 3. Circadian chromopharmacologic modulation of dose-response relationshipgs in rodents and in men
- A. Reinberg / F. Levi
- Download
- 11. Dose-response and registration of new drugs
- R. Temple
- Download
- 19. Pharmacological dose-response curves in gastrointestinal therapy
- TR. Weihrauch / P. Demol
- Download
- 4. Dose-response relationships in normal versus diseased subjects
- M. Orme
- Download
- 12. Dose-response relationship in respect of biochemical effects of drugs and the problem of adaptive responses
- DG. Grahame-Smith
- Download
- 20. Dose-response relationships in antimicrobial therapy
- AM. Geddes
- Download
- 5. Pharmacokinetic modulation of the dose-response relationship
- JG. Baxter / JA. Barnett / D. Lalka
- Download
- 13. Effect of age in the dose response curve
- P. Lucio
- Download
- 21. Dose response relationships in pshychopharmacology
- LF. Gram
- Download
- Dose-response relationships in clinical pharmacology Preface
- L. Lasagna / S. Erill / CA. Naranjo
- Download
- 6. Considerations of dose-response with centrally-acting drugs
- A. Nicholson / PA. Pascoe / MB. Spencer
- Download
- 14. Dose-response relationship and therapeutic drug monitoring
- E. Perucca / F. Pisani
- Download
- 22. The relation between dose and response to diagnostic drugs
- EA. Carr Jr. / JM. Gona / M. Carroll / RJ. Kurland
- Download
- Dose-response relationships in clinical pharmacology List of participants
- Download
- 7. Dose-response relationships in drug dependence in humans
- CA. Naranjo / UE. Busto
- Download
- 15. An epidemiological approach to dose-response relationship
- U. Busto / CA. Naranjo
- Download
- Dose-response relationships in clinical pharmacology Contents
- Download
- 8. The dose-response curve in indirectly acting drugs
- P. du Souich / P. Larochelle / S. Marleau / J. Cusson
- Download
- 16. Dose response effects in analgesiometry: clinical vs experimental pain
- HJ. McQuay
- Download
