Author
P. du Souich / D. Lalka
Around 30 articles which contributed in an exceptional manner to the huge progress of pharmacokinetics are included in the second volume of Pharmacotherapy Revisited: an Esteve Foundation Series, under the title Pharmacokinetics: development of an exquisitely practical science. This time, the most relevant articles were selected by Patrick du Souich, from the Department of Pharmacology of the University of Montreal. This publication is destined for all professionals interested in knowing the grounds of pharmacokinetics.
| Full document | ||
| Full PDF | P. du Souich / D. Lalka | [wpdm type=”btn3″] |
| Chapters | ||
| Acknowledgements | [wpdm id=17 type=”btn”] | |
| Introduction | P. du Souich / D. Lalka | [wpdm id=19 type=”btn”] |
| Index | [wpdm id=18 type=”btn”] | |
| 1. Studies on digitalis in ambulatory cardiac patients. II. The elimination of digitalis in man | H. Gold / AC. DeGraff | [wpdm type=”btn3″] |
| 2. Studies on antibacterial action of sulfonamide drugs. III. Correlation of drug activity with binding to plasma proteins | BD. Davis / WB. Wood Jr | [wpdm type=”btn3″] |
| 3. Fate of procaine in the human body after subarachnoid injection | A. Goldberg / H. Koster / R. Warshaw | [wpdm type=”btn3″] |
| 4. The pharmacological basis for the rational use of atabrine in the treatment of malaria | JA. Shannon / DP. Earle / BB. Brodie / JV Taggart / RW Berliner / Resident Staff of the Research Service | [wpdm type=”btn3″] |
| 5. The effect of sodium bicarbonate on the serum salicylate level | K. Smull / R. Wégria / J. Leland | [wpdm type=”btn3″] |
| 6. Theophylline blood levels after oral, rectal and intravenous administration, and correlation with diuretic action | EB. Truitt Jr / VA. McKusick / JC. Krant Jr | [wpdm type=”btn3″] |
| 7. Metabolism of theophylline (1,3-dimethylxanthine) in man | BB. Brodie / J. Axelrod / J. Reichenthal | [wpdm type=”btn3″] |
| 8. Enzymatic oxidation of pentobarbital and thiopental | JR. Cooper / BB. Brodie | [wpdm type=”btn3″] |
| 9. The relation between dose of succinylcholine and duration of apnea in man | W. Kalow / DR. Gunn | [wpdm type=”btn3″] |
| 10. Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline | GP. Quinn / J. Axelrod / BB. Brodie | [wpdm type=”btn3″] |
| 11. A comparison of the analgesic and respiratory effects of dihydrocodeine and morphine in man | JC. Seed / SL. Wallenstein / RW. Houde / JW. Bellville | [wpdm type=”btn3″] |
| 12. On the mechanism of intestinal absorption of drugs | CAM. Hogben / DJ. Tocco / BB. Brodie / LS. Schanker | [wpdm type=”btn3″] |
| 13. Kinetics of penetration of drugs and other foreign compounds into cerebrospinal fluid and brain | S. Mayer / RP. Maickel / BB. Brodie | [wpdm type=”btn3″] |
| 14. Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs | AH. Conney / C. Davison / R. Gastel / JJ. Burns | [wpdm type=”btn3″] |
| 15. Genetic control of isoniazid metabolism in man | DA. Price Evans / KA. Manley / VA. McKusick | [wpdm type=”btn3″] |
| 16. Kinetics of drug metabolism by hepatic microsomes | A. Rubin / TR. Tephly / GJ. Mannering | [wpdm type=”btn3″] |
| 17. Kinetic analysis of blood levels and urinary excretion in the absorptive phase after single doses of drug | JG. Wagner / E. Nelson | [wpdm type=”btn3″] |
| 18. Drug interactions in man. I. Lowering effect of phenobarbital on plasma levels of bishydroxycoumarin (Dicumarol) and diphenylhydantoin (Dilantin) | SA. Cucinell / AH. Conney / M. Sansur / JJ. Burns | [wpdm type=”btn3″] |
| 19. Kinetics of pharmacologic effects | G. Levy | [wpdm type=”btn3″] |
| 20. Methotrexate pharmacokinetics | KB. Bischoff / RL. Dedrick / DS. Zaharko / JA. Longstreth | [wpdm type=”btn3″] |
| 21. Drug distribution and pharmacologic effects | M. Gibaldi / G. Levy / H. Weintraub | [wpdm type=”btn3″] |
| 22. Protein binding of diphenylhydantoin and desmethylimipramine in plasma from patients with poor renal function | MM. Reidenberg / I. Odar-Cederlöf / C. von Bahr / O. Borga / F. Sjöqvist | [wpdm type=”btn3″] |
| 23. Drug therapy. Serum drug concentrations as therapeutic guides | J. Koch-Weser | [wpdm type=”btn3″] |
| 24. A physiological approach to hepatic drug clearance | GR. Wilkinson / DG. Shand | [wpdm type=”btn3″] |
| 25. Reversal of advanced digoxin intoxication with FAB fragments of digoxin-specific antibodies | TW. Smith / E. Haber / L. Yeatman / VP. Butler | [wpdm type=”btn3″] |
| 26. Polymorphic hydroxylation of debrisoquine in man | A. Mahgoub / JR. Idle / LG. Dring / R. Lancaster / RL. Smith | [wpdm type=”btn3″] |
| 27. Enhancement of the bioavailability of propranolol and metoprolol by food | A. Melander / K. Danielson / B. Schersten / E. Wahlin | [wpdm type=”btn3″] |
| 28. Plasma protein binding of basic drugs. II. Importance of alpha1-acid glycoprotein for interindividual variation | KM. Piafsky / O. Borga | [wpdm type=”btn3″] |
| 29. Estimation of population characteristics of pharmacokinetic parameters from routine clinical data | LB. Sheiner / B. Rosenberg / VV. Marathe | [wpdm type=”btn3″] |
| 30. Effect of plasma protein and tissue binding on the biologic half-life of drugs | M. Gibaldi / G. Levy / PJ. McNamara | [wpdm type=”btn3″] |
| 31. Understanding the dose-effect relationship: Clinical application of pharmacokinetic-pharmacodynamic models | NH. Holford / LB. Sheiner | [wpdm type=”btn3″] |
| 32. Stereoselective metabolism of mephenytoin in man | A. Küpfer / RK. Roberts / S. Schenker / RA. Branch | [wpdm type=”btn3″] |
