Autor
Que cada paciente es diferente ante un tratamiento supone un obstáculo pero a la vez un reto para la farmacología. Durante el octavo simposio internacional organizado por la Fundación Dr. Antonio Esteve se trataron diversos aspectos relacionados con la diversidad de respuestas a los fármacos. Geoffrey T. Tucker, del Departamento de Farmacología Molecular y Farmacogenéticos de la Universidad de Sheffield, es el editor de este volumen número 8 de la serie Esteve Foundation Symposia, publicado por Elsevier Science.
Capítulos | ||
Introduction | G. Tucker | [wpdm id=240 type=”btn”] |
List of participants | [wpdm id=241 type=”btn”] | |
1. Pharmacokinetic / pharmacodynamic impact of genetic polymorphism of drug metabolizing enzymes | H.K. Kroemer / W. Siegmund | [wpdm id=217 type=”btn”] |
2. Clinical Aspects of Polymorphic Drug Metabolism | G.T. Tucker | [wpdm id=218 type=”btn”] |
3. Enzyme Inhibition and Induction – PK/PD Impact | U. Klotz / K.T. Kivistö | [wpdm id=219 type=”btn”] |
4. Adverse drug reactions: role of enzyme inhibition and induction | M. Pirmohamed / B. Kevin Park | [wpdm id=220 type=”btn”] |
5. Approaches to studying the role of transporters in drug interactions in man | P.B. Watkins | [wpdm id=221 type=”btn”] |
6. Genetic polymorphisms in cardiovascular disease: focus on renin angiotensin system | G.K. Davis / N.H. Naqvi | [wpdm id=222 type=”btn”] |
7. Pharmacogenetics of respiratory system drugs | I.P. Hall | [wpdm id=223 type=”btn”] |
8. Tolerance as a Modulator of Drug Response | N.L. Benowitz | [wpdm id=224 type=”btn”] |
9. Variability in human drug response. Age as a source of variability | M.T. Kinirons | [wpdm id=225 type=”btn”] |
10. Gender as a source of variability in human pharmacokinetics and pharmacodynamics | P. Rolan / L. McKeown | [wpdm id=226 type=”btn”] |
11. Ethnic differences in drug response: A model for understanding interindividual variability | A.J.J. Wood | [wpdm id=227 type=”btn”] |
12. Effect of disease on the pharmacokinetic and pharmacodynamic determinants of response to diuretics | D. Craig Brater | [wpdm id=228 type=”btn”] |
13. Effects of exercise on human drug response | M.A. van Baak | [wpdm id=229 type=”btn”] |
14. Benefit risk evaluation of medicinal products – an epidemiological approach | C. Martinez | [wpdm id=230 type=”btn”] |
15. Pain – How to standardize a subjective measure | E. Anneli Kalso | [wpdm id=231 type=”btn”] |
16. Variable patient compliance as a source of variability in drug response | J. Urquhart | [wpdm id=232 type=”btn”] |
17. Placebo Response | M. Lader | [wpdm id=233 type=”btn”] |
18. Pharmacogenetic basis of variation in drug dependence | E.M. Sellers / M.K. Romach / R.F. Tyndale | [wpdm id=234 type=”btn”] |
19. Role of phenotyping and genotyping in the measurement of variability in human drug response | J. Benítez | [wpdm id=235 type=”btn”] |
20. Population Modelling | L. Aarons | [wpdm id=236 type=”btn”] |
21. Can we design drugs with low variability | D. Smith | [wpdm id=237 type=”btn”] |
22. Management of variability through dosage form design | P. du Souich / A.O.S. El-Kadi / A.M. Bleau | [wpdm id=238 type=”btn”] |
23. Management of Variability – Regulatory Aspects | T. Salmonson / J.R. Wade | [wpdm id=239 type=”btn”] |
- 2. Clinical Aspects of Polymorphic Drug Metabolism
- G.T. Tucker
- Descargar
- 10. Gender as a source of variability in human pharmacokinetics and pharmacodynamics
- P. Rolan / L. McKeown
- Descargar
- 18. Pharmacogenetic basis of variation in drug dependence
- E.M. Sellers / M.K. Romach / R.F. Tyndale
- Descargar
- 3. Enzyme Inhibition and Induction - PK/PD Impact
- U. Klotz / K.T. Kivistö
- Descargar
- 11. Ethnic differences in drug response: A model for understanding interindividual variability
- A.J.J. Wood
- Descargar
- 19. Role of phenotyping and genotyping in the measurement of variability in human drug response
- J. Benítez
- Descargar
- 4. Adverse drug reactions: role of enzyme inhibition and induction
- M. Pirmohamed / B. Kevin Park
- Descargar
- 12. Effect of disease on the pharmacokinetic and pharmacodynamic determinants of response to diuretics
- D. Craig Brater
- Descargar
- 20. Population Modelling
- L. Aarons
- Descargar
- 5. Approaches to studying the role of transporters in drug interactions in man
- P.B. Watkins
- Descargar
- 13. Effects of exercise on human drug response
- M.A. van Baak
- Descargar
- 21. Can we design drugs with low variability
- D. Smith
- Descargar
- 6. Genetic polymorphisms in cardiovascular disease: focus on renin angiotensin system
- G.K. Davis / N.H. Naqvi
- Descargar
- 14. Benefit risk evaluation of medicinal products - an epidemiological approach
- C. Martinez
- Descargar
- 22. Management of variability through dosage form design
- P. du Souich / A.O.S. El-Kadi / A.M. Bleau
- Descargar
- Variability in human drug response Introduction
- G. Tucker
- Descargar
- 7. Pharmacogenetics of respiratory system drugs
- I.P. Hall
- Descargar
- 15. Pain - How to standardize a subjective measure
- E. Anneli Kalso
- Descargar
- 23. Management of Variability - Regulatory Aspects
- T. Salmonson / J.R. Wade
- Descargar
- Variability in human drug response List of participants
- Descargar
- 8. Tolerance as a Modulator of Drug Response
- N.L. Benowitz
- Descargar
- 16. Variable patient compliance as a source of variability in drug response
- J. Urquhart
- Descargar
- 1. Pharmacokinetic / pharmacodynamic impact of genetic polymorphism of drug metabolizing enzymes
- H.K. Kroemer / W. Siegmund
- Descargar
- 9. Variability in human drug response. Age as a source of variability
- M.T. Kinirons
- Descargar
- 17. Placebo Response
- M. Lader
- Descargar