11th Award: A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

The epigenetics laboratory of the National Cancer Research Center (Centro Nacional de Investigaciones Oncológicas) (CNIO) published in Nature Genetics in 2006 the discovery of the mutation in an epigenetic gene in human cancer. Three years later, received the eleventh Esteve Foundation Research Award for an article in which they described the alteration of the HDAC2…